Discussion 'New treatments'
UltraCAR-T Therapy – Scope & Possibilities in Multiple Myeloma Management
Ongoing clinical trials are investigating the safety and efficacy of a new type of CAR T (Chimeric antigen receptor T-cells) therapy called UltraCAR-T therapy for myeloid malignancies. Unlike current CAR T cells, which utilize viruses to attach the CAR to…
Understanding mRNA Covid-19 Vaccines
Messenger RNA vaccines, also called mRNA vaccines, are some of the first COVID-19 vaccines authorized for use in the United States. mRNA vaccines are a new type of vaccine to protect against infectious diseases. They teach the cells of our…
Melflufen for Myeloma: A Deep Dive
The FDA recently granted priority review to a new drug application for melflufen (INN melphalan flufenamide), in combination with dexamethasone. Melflufen is intended for use as a first choice for patients with multiple myeloma whose disease is refractory to at…
ASH 2020 Updates: CAR T Cell Therapies in Multiple Myeloma
We kickstart the new year with a discussion on CAR T cells in myeloma treatment with a focus on the CT053, a CAR T-cell therapy targeting the BCMA protein and granted orphan drug status by the U.S. Food and Drug…
Expanding Male Contraceptive Options: Study Investigating A New Contraceptive Gel
Men who wish to control their fertility currently have limited options. They have to rely on their female partner using contraceptives, use condoms, undergo vasectomy, or abstain. The male contraceptive study being discussed is testing a gel as a possible…